How do I dynamically enable or disable config nodes?

Understood... but enable/disable is just a workaround.

As your issue is with rs485/modbus multi-device management/communication ..you may have to re-post towards RS485/Modbus topic :wink: I'm sure there will be some experts to help you with the root cause

e.g. here or here or here

It looks like others have solved the multi-device issues