Before re-deploy i want to clear global variable

Before re-deploy i want to clear global variable content how to do that ?

You can delete it manually in the Context side-bar or by using an Inject and Change node.

However, there are no runtime events available to trigger a flow automatically.

Make sure that you do a full deploy, that clears all in-memory variables I think.
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I believe you can also use JS in a function node:

global.set('variableName',undefined);