You can do this by indicating to Telegram that it should use markdown enhanced messages. The markup is very limited but you can do bold, italic and fixed-width font.
On my generic Telegram output flow, I use a simple JSONata change node to change the payload before sending:
{
"chatId": chatId,
"content": "*" & $replace(topic, "_", " ") & "*\n" & $join($split(payload, "<br>"), "\n"),
"type": contentType,
"options": {
"parse_mode": "Markdown"
}
}