The directory you point to has to be created first.
For example if you specify "MMMlogs" in the Log Dir settings, it will point to a directory in your home folder. On a linux system that folder will be "/home/your_username/MMMlogs". Remember that you have to create it first.
Don't use the ~ in the Log Dir because it's implied. You could put a full path like "/var/log/MMMlogs" - but remember to create the directory first.