No problem.
WSL is a virtual Linux environment running under Windows 10. So you get a lightweight VM effectively.
So you can use WSL like any other Linux environment. Install node.js (and a version manager if you want to), then install Node-RED, etc.
Interestingly, I no longer use PuTTY - actually KiTTY - to connect to my Pi's. I use WSL with SSH command line client with a Windows shortcut to fire it up. This is actually faster! Go figure.
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