Sorry, but I cannot understand this.
Q1: What is the IP, Gateway and Mask of the PLC?
Q2: What is the IP, Gateway and Mask of the computer where Node-RED is running?
Q3: Show me what "Open Settings" you have in the FX3u PLC
Q4: Show me a screen shot of the MC Protocol config node as you have set it up in Node-RED
NOTE:
I have 20y experience of Mitsi PLCs + data collection. I can pretty much predict your life every 2~4 weeks - you will be resetting the PLC because the TCP connection has locked up. I strongly recommend UDP connection instead.